Closing Soon
Prevention as prevention of Eczema in infants, sponsored by Dr Kristin Wickens
Get in touch This trial recruits from December 2012 for 54 weeks
Prof Professor Julian Crane
Phone: +64 04 918 5258
Fax: +64 4 389 5427
Email: julian.crane@otago.ac.nz
Address:
Wellington Asthma Research Group
Wellington School of Medicine and Health Sciences
University of Otago
P O Box 7343
Wellington South 6242
Inclusion Criteria
Gender: Females
A woman will be eligible if 1. either they or the infant's father has a history of asthma, eczema or allergic rhinitis treated by a doctor, and the mother 2. is 14-16 weeks gestation and 3. intends to breastfeed.
Exclusion Criteria
A woman will be ineligible if she 1. has a serious immunological disorder or is using immunomodulatory drugs 2. is currently using or intends to use probiotics themselves or in their child 3. is participating in another RCT 4. has known cardiac vavle disease for which antibiotic prophylaxis is required if undergoing dental procedures 5. required IVF to establish this pregnancy 6. has a pre-enrolment scan showing fetal abnormalities 7. does not agree to GP, midwife or hospital staff notification 8. has a severe allergy to cow's milk that requires her to carry adrenalin 9. has a history of transplant 10. has a history of HIV 11. is on continuous long-term antibiotics 12. does not speak English
ACTRN12612000196842
A randomized placebo controlled trial of the effects of the probiotic Lactobacillus rhamnosus HN001 taken from the 1st trimester of pregnancy till 6 months post partum, if breastfeeding, on the development of eczema and atopic sensitization in infants by age 12 months.
A maternal probiotic intervention for infant allergic disease prevention